Fallout 76 Guide: All the details on Mutations

The world of Fallout 76 is doused with radiation, and where there is radiation, there are also genetic mutations. Even the player can see their DNA changed: this is a condition with pros and cons, and we want to explain to you exactly what you are facing, so as not to leave you unprepared.

Mutations are a status effect that changes some character attribute values. The methods related to obtaining and eliminating a mutation are simple; getting and keeping the right ones, on the other hand, is a different kettle of fish altogether.



Read also: Fallout 76 Review, Bethesda's most controversial title

How to get a mutation

Mutations are the direct result of a large dose of radiation. The more radiation you receive, the more likely you are to get a mutation: however, the nature of this is defined in a completely random way. Basically, every element that produces radiation has a chance to give the player a mutation. Some examples:

  • Drink unpurified water
  • Swim in radiated water
  • Touching petrified corpses
  • Stay near toxic waste
  • Staying close to a nuclear fallout
  • Being attacked by toxic monsters

How to cure a mutation

Mutations are permanent until such time as they are cured. If the mutations obtained are not to your liking, it is possible to eliminate them with a couple of methods:

  • Usare un RadAway
  • Use a decontamination arch

Fallout 76 Guide: All the details on Mutations

How to avoid mutations

Since mutations are related to radiation, the primary way to avoid them is to avoid radiation as well. In addition to staying away from the aforementioned elements (waterways, unpurified food and drink ...) and wearing equipment that limits the accumulation of radiation, it's a great idea to keep radiation to a minimum, as the greater the amount of health that the latter eliminates, the higher the likelihood of obtaining a mutation.



In addition, there is the “Starched Genes” perk card. It is not possible to obtain (or lose) mutations through this card, regardless of the amount of radiation suffered.

How to maintain a mutation

Sometimes maintaining a mutation is convenient. While each carries negative effects, the positive ones often far outweigh them. Many players, therefore, will want to keep them tight but at the same time want to get rid of the damage to their health.

Read also: Fallout 76 Guide: level up, SPECIAL and Perk Cards

The best method is therefore heal with a RadAway but only after equipping the "Starched Genes" perk card. As mentioned above, it not only serves to block the obtaining of mutations, but also to prevent them from being eliminated by a cure.

All mutations and their effects

Let's now see a list of all available mutations and what their effects are:

  • Adrenaline Reaction: Deal more damage when health is low, but lose 50 maximum health
  • Hollow Bones: +4 to Agility, falling slower, taking less damage when falling, but getting -4 to Strength
  • Carnivore: the effect obtained by eating meat is doubled and no diseases are obtained, but eating vegetables has no effect
  • Chameleon: if you are stationary and unarmed you become invisible
  • Eagle Eyes: +4 to Perception and 25% more critical damage, but -4 to Strength
  • Egg Head: +6 Intelligence, but gains -3 Strength and -3 Stamina
  • Electrically Charged: You deliver an electric shock when hit by a melee attack, but take a small amount of damage

Fallout 76 Guide: All the details on Mutations


  • Empathic: Team members take 25% less damage, but you take 33% more damage
  • Landed: +100 energy resistance, but damage from energy weapons is reduced
  • Regenerative Factor: + 300% health regeneration is gained, but the effect of healing items is reduced by 55%
  • Herbivorous: the effect obtained by eating vegetables is doubled and no diseases are obtained, but eating meat has no effect
  • Pack Mentality: +2 to all stats when on a team, but -2 to all stats when alone
  • Marsupial: +20 to carry weight and increase in height reached with a jump, but -4 to Intelligence
  • Walking Plague: A poisonous aura is gained that increases in potency for each disease possessed, but these still take effect
  • Scaly Skin: +50 damage and energy resistance, but gain -50 Action Points
  • Speed ​​Demon - Move and reload 20% faster, but hunger and thirst rise faster
  • Claws: Bare-handed attacks do 25% more damage and cause bleeding, but you get -4 to Agility
  • Twisted Muscle: Melee attacks do 25% more damage and have a chance to incapacitate opponents, but firearms are less accurate
  • Unstable Isotope: You release a beam of radiation when hit by a melee attack, but you also take a little damage

Read also: Fallout 76 Guide: CAMP construction and placement



This concludes our guide to Fallout 76 mutations. Tell us: which of these mutations could you find most useful?

Mutations are an interesting RPG component, one more reason to buy Fallout 76 and have fun creating a unique PC.

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